Did NHK, Japan’s PBS, Violate Human Rights of Obokata (小保方 晴子) over STAP?

Obokata press conference

Obokata late press conference

The Japanese public broadcasting system, NHK, has been accused by scientist Haruko Obokata of violating her human rights.

Obokata was the primary researcher involved in the STAP cell fiasco in which two ultimately retracted Nature papers contained duplicated, plagiarized, and manipulated data. She was certainly not the only researcher on those papers, but overall she has been accused of having the most central role in the STAP problems. Obokata left RIKEN late in 2014.

During the height of the STAP cell mess the Japanese media hounded Obokata and other STAP cell authors including Yoshiki Sasai, who ultimately committed suicide. From accounts in Japan, the STAP cell story was on the equivalent of the nightly news and on the front of national newspapers and tabloids almost every day for a time.

For instance, NHK was incredibly persistent with pursing Obokata and now Obokata has said that they violated her human rights in a complaint to the Japanese Broadcasting Ethics & Program Improvement Organization or BPO. Obokata asserts that NHK violated her rights in numerous ways including accusing her of stealing embryonic stem cells and she sustained injuries while being pursued by NHK. BPO will be investigating these and other assertions by Obokata against NHK.

During the STAP cell mess last year, it seems because I was covering the STAP cell claims and science here on this blog, many members of the Japanese media emailed and called me. I can understand that they were looking for information and perspectives, but it went out of control in certain cases. Some, including reporters saying they were from NHK, were very aggressive with me. They some persistently called me at work and even at home in the middle of the night.

I had decided to not talk with them because of their aggressiveness and their tendency to focus on negative, personal stories rather than the science and facts, but they wouldn’t take “no” for an answer. Several pursued me for comment at conferences too. I don’t have direct knowledge of what happened with Obokata and NHK, but my sense is that the media went way out of bounds on STAP and made it personal.

Haruko Obokata 小保方 晴子-like Game Character Conducts ‘Dangerous Research’

I’ve seen many crazy things over the years doing this blog.

There was the Moriguchi IPS cell fraud, the electric stem cell bra, the stem cell supermodel case, the stem cell soup No. 7 aphrodisiac, the STAP cell scandal….and the craziness goes on.

Today there’s a new one that even surprised me.

Haruko Obokata, lead STAP cell author, has now entered the online game world, although it seems not of her own choosing.

The Asahi Shimbun reports that a new character in the video game Star Galaxy, “Haruko Oppenheimer” bears a striking resemblance to Obokata. Presumably this name is a mash up of Haruko Obokata and Robert Oppenheimer of the Manhattan Project that made the first atomic bombs.

Gamers noticed the virtual Obokata. See image here for yourself.

Obokata was known for decorating her lab with cute cartoon-like characters as well (see one on her incubator).

Obokata game

In the Star Galaxy online game, Haruko Oppenheimer was conducting “dangerous research” under the theme “ultimate cell”. Not sure what that means exactly, but it sure seems like a reference to STAP cells.


Game maker Square Enix, apologized and changed the character’s name to “Jesca Fred”, but not her appearance.

Obokata is now officially immortalized in pop culture.

Perspectives on final RIKEN report on STAP cell scandal & what comes next

STAP cells FigureThe Japanese research institute RIKEN has come full circle in a way on the STAP cell scandal. Note that the STAP papers included not only authors from RIKEN, but also from Brigham and Women’s Hospital/Harvard Medical School.

With its final report released today (also a powerpoint of images were released including the one showing a figure posted here of reportedly made up data published in a STAP paper), RIKEN seems to now have handled this complicated mess in a relatively rigorous, scientific manner that paves the way for moving on from it.

What would you have done in RIKEN’s shoes? It’s not a pleasant thing to contemplate.

As a research institution, what do you do if a potential major scientific scandal is cropping up under your roof? It’s unpredictable and dangerous and couldn’t have come at a worse time for RIKEN. So how do you handle it? What would you have done?

RIKEN was faced with this kind of unpleasant reality early this year. A very high moment for RIKEN with the publication of two seemingly groundbreaking Nature papers including numerous RIKEN authors quickly headed the other direction and began unraveling.

By February, only weeks after the STAP cell papers were published supposedly reporting the creation of power stem cells called “STAP cells”, there were signs that the research was plagued with profound problems including signs of potential misconduct.

At that point in February and March, what should the leaders at RIKEN do/have done? I’m sure they were asking themselves this tough question.

There have been ups and downs as to how RIKEN has handled STAP, but in the new report there are indications of a sober, objective and more thorough approach to STAP. I think this is a positive, constructive step even if the conclusions are negative and sad.

Dennis Normile has a nice summary over at Science News of the RIKEN report:

“The committee determined that 3 supposed STAP stem cell lines were actually likely to be 3 previously existing embryonic stem (ES) cell lines. “It is unlikely that there was accidental contamination by three different ES cells, and it is suspected that the contamination may have occurred artificially…”

This new RIKEN report on STAP has concluded that what were claimed to be STAP cells were almost certainly embryonic stem cells (ESCs) instead. It cannot be sure if the ESCs were intentionally and fraudulently used, but it says that is probable. If it was done on purpose RIKEN also cannot be sure who did it.

The report concludes that STAP first author Haruko Obokata, who RIKEN earlier had determined committed certain STAP-related misconduct, committed additional misconduct over certain data, but the report also lays some of the blame for STAP to lack of proper supervision by senior STAP authors Yoshiki Sasai, Teruhiko Wakayama, and Hitoshi Niwa. One remaining thing we do not know is what this report means for Wakayama or Niwa, the latter still being at RIKEN.

So what does all of this mean and where do things go from here?

While there is still some more to resolve on the Japan side of STAP, my impression is that this report along with Obokata’s resignation allows for RIKEN to really begin to move on from STAP.

Normile’s article concludes pointing towards where the STAP-related focus may turn next:

One of the papers’ co-authors has been beyond the reach of RIKEN investigators: Charles Vacanti, a tissue engineer at Brigham and Women’s Hospital in Boston, an affiliate of Harvard Medical School. Obokata initiated her work on STAP cells while a post-doc in Vacanti’s lab. Mutsuhiro Arinobu, a RIKEN executive director, said that although they have been in contact with Harvard, input from Vacanti “is not included in this investigation.”

Harvard and Brigham and Women’s Hospital may or may not be conducting STAP investigations of their own. However, certainly at this point relatively speaking key unanswered questions remain on the Harvard side of STAP.

Do You Believe in STAP Stem Cells? One Final Poll in 2014

It’s been many months since I last asked, so for one last time in 2014, here’s a poll on your views of STAP stem cells.

What do you think? You can vote once per day. I am going to follow up with a couple different STAP-related polls this week, but this is the last one of 2014 on the actual STAP cells.

Newly Update Comprehensive STAP Cell Timeline with Key Events & Links

Here is an updated timeline for the major events (and links) for the STAP fiasco. If you think absolutely critical events are missing, let me know in the comments and I’ll consider adding them.

Jan 29Nature publishes STAP papers online
Jan 29Postpub review of papers on ipscell.com
Jan 30First STAP polling starts: respondents mostly positive
Feb 2Surprising interview w/Vacanti: STAP easy to make, same as spore cells
Feb 4First key Pubpeer comment on splicing in Figure 1i
Feb 6Top 5 reasons for doubts on STAP
Feb 7STAP crowdsourcing experiment starts
Feb 13First Pubpeer comment on STAP placenta issue
Feb 13JuuichiJigen first post on STAP problems
Feb 14RIKEN & Nature begin STAP investigations
Feb 27Wakayama interview
Mar 10Wakayama calls for STAP paper retraction
March 13JuuichiJigen post on Obokata Ph.D. thesis problems
March 14RIKEN alleges that Obokata committed misconduct
Mar 24Nature rejects Ken Lee’s STAP paper showing that STAP doesn’t work
Apr 1Vacanti Harvard STAP talk for this fateful day was cancelled
Apr 1RIKEN announces Obokata guilty of misconduct
Apr 9Obokata admits mistakes, but not misconduct
April 25Head of RIKEN STAP investigation committee, Shunsuke Ishi, resigns amid allegations of his own paper problems
May 8F1000 Publishes Lee Lab Paper showing STAP fails
May 27Call for Nature retraction of STAP papers
May 28Obokata OKs letter, but not article retraction
Jun 3Obokata agrees to retract STAP article too
June 12External committee (chaired by Teruo Kishi) issues report calling for zero-based restructuring of Riken Center for Developmental Biology (CDB), the institute with which Obokata, and co-authors Yoshiki Sasai and Hitoshi Niwa are affiliated, and where co-author Teruhiko Wakayama was formerly affiliated
Jun 16Genetics data suggest STAP cells involved mix or switch
July 2STAP Nature papers retracted
August 5Tragically, one of the scientists involved in STAP, Yoshiki Sasai, commits suicide
September 3Vacanti & Kojima reaffirm absolute confidence in STAP but issue new STAP protocol
December 19Obokata and Niwa fail in STAP final replication effort
December 20Obokata resigns from RIKEN
September 23, 2015Nature publishes refutations of STAP